Phosphoinositides in phagocytosis and macropinocytosis - ScienceDirect
摘要:
Phagocytosis is essential for innate immunity and for the clearance of apoptotic bodies.Macropinocytosis plays a central role in antigen presentation, coupling innate and acquired immunity.Phosphoinositides play pivotal roles in both phagocytosis and macropinocytosis.Phosphoinositides signal the cytoskeletal and membrane remodeling events that underlie phagosome and macropinosome formation.The subsequent maturation of phagosomes and macropinosomes is also regulated by phosphoinositides.
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DOI:
10.1016/j.bbalip.2014.09.005
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年份:
2015
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