Early antigen-specific response by naive CD8 T cells is not altered with aging
摘要：
Both a dramatic decline in CD8 responses and a switch to memory T cell predominance occur with aging. The extent to which the loss of responsiveness is the consequence of the accumulation of more differentiated vs intrinsically defective T cells (or both) has been unclear. Using similar conditions of Ag stimulation, we have examined the responses generated by CD8
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关键词：
immune complexes Fc gamma receptors DC maturation inhibitory/activating receptor pairs T cell immunity
DOI：
10.4049/jimmunol.168.12.6120
被引量：
年份：
2002
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