摘要：

Disclosed are compounds of formula (1.0) wherein R<13> represents an imidazole ring; R<14> represents a carbamate, urea, amide or sulfonamide group; R<8> represents H when the alkyl chain between the amide group and the R<13> imidazole group is substituted, or R<8> represents a substituent such aa arylalkyl, heteroarylalkyl or cycloalkyl; and the remaining substituents are as defined herein. Also disclosed are compounds wherein R<8> is H, and the alkyl chain between the amide group and the R<13> imidazole group is unsubstituted. Also disclosed is a method of treating cancer and a method of inhibiting farnesyl protein transferase using the disclosed compounds.

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