Assessing low levels of high-density lipoprotein cholesterol as a risk factor in coronary heart disease: a working group report and update.
摘要：
Clinical data show that a 1% increase in serum concentrations of high-density lipoprotein cholesterol (HDL-C) can decrease cardiovascular risk by 2% to 3%. Therefore, mechanisms affecting the level and functionality of high-density lipoprotein (HDL) and its constituents are being investigated as targets for the rational development of drugs to prevent or treat cardiovascular disease. High-density lipoprotein-related research may also increase our understanding of the link between atherosclerosis and metabolic disorders. This report and update of the HDL Working Group discusses HDL metabolism and reverse cholesterol transport, impaired HDL as a marker and a cause of proatherogenic states, and experimental and current approaches to HDL-related therapy.
展开
关键词：
apo apolipoprotein CETP cholesteryl ester transfer protein CHD coronary heart disease FCR fractional catabolic rate HDL-C high-density lipoprotein cholesterol
DOI：
10.1016/j.jacc.2003.08.061
被引量：
年份：
2004
Elsevier
(全网免费下载)
Taylor & Francis
Elsevier
Semantic Scholar
(全网免费下载)
万方医学
查看更多
dx.doi.org
NCBI
Europe PMC
NCBI
Oxford Univ Press
ResearchGate
ResearchGate
(全网免费下载)
ProQuest
EBSCO
deepdyve.com
pubfacts.com
www.socolar.com
circgenetics.ahajournals.org
onacademic.com
circ.ahajournals.org
(全网免费下载)
mendeley.com
readcube.com
aggjournal.com
content.onlinejacc.org
onlinejacc.org
(全网免费下载)
jlr.org
cghjournal.org
scienceopen.com
mysciencework.com
circ.ahajournals.org
(全网免费下载)
pharmrev.aspetjournals.org
jaccjournaloftheacc.com
Elsevier
(全网免费下载)
Semantic Scholar
(全网免费下载)
ResearchGate
(全网免费下载)
circ.ahajournals.org
(全网免费下载)
circ.ahajournals.org
(全网免费下载)
onlinejacc.org
(全网免费下载)
通过文献互助平台发起求助，成功后即可免费获取论文全文。
相似文献
参考文献
引证文献
辅助模式
引用
文献可以批量引用啦~
欢迎点我试用！
