Structured orthoester and orthocarbonate drug delivery devices
申请(专利)号:
US05/882814
申请日期:
19780302
公开/公告号:
US04131648A
公开/公告日期:
19781226
申请(专利权)人:
ALZA CORPORATION
被引量:
摘要:
The invention concerns orthoester and orthocarbonate polymers having a repeating mer comprising a hydrocarbon radical and a symmetrical dioxycarbon unit of the general formula: ##STR1## WHEREIN R.sub.1 is a multivalent hydrocarbon radical, R.sub.2 and R.sub.3 are hydrocarbon radicals with at least one of R.sub.2 or R.sub.3 bonded to the dioxycarbon through an oxygen linkage, and which polymers are synthesized by reacting a polyol with an orthoester or orthocarbonate. The polymers are useful for making articles of manufacture, including devices and coatings for delivering beneficial agents.
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