Boosting Tyrosinase Inhibiting Activity of Skin Whitening and Sunscreen Compositions

阅读量:

33

申请(专利)号:

US20030248817

申请日期:

2003-02-21

公开/公告号:

US2004166069A1

公开/公告日期:

2004-08-26

申请(专利权)人:

GUPTA SHYAM K.

发明人:

SK Gupta

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被引量:

117

摘要:

The present invention relates to boosting of the skin whitening benefits of commonly used tyrosinase inhibitors, tyrosinase competitors, and melanin and other color bodies' reducing agents. The activity of such compositions can be synergistically enhanced by the inclusion of at least one antioxidant composition. This synergistic benefit is further increased if a UV-inhibitor or UV-absorber is also included in such compositions. This is both unexpected and surprising because most such tyrosinase inhibitors, tyrosinase competitors, or melanin reducing agents are also known to possess antioxidant and UV-absorbing properties. Thus, the skin whitening benefits are synergistically increased by combining at least one of the following; (i) a tyrosinase inhibiting agent, or (ii) a tyrosinase competing agent, or (iii) a melanin reducing agent, or (iv) combinations thereof; with at least one antioxidant composition. The additional inclusion of at least one UV inhibitor or absorber composition provides further enhancement of skin whitening effects from such tyrosinase inhibiting, tyrosinase competing or melanin reducing agents that are formulated in combination with an antioxidant composition. In a related application, the skin whitening property of a sunscreen composition can be boosted by the inclusion of an antioxidant composition and a tyrosinase inhibitor, tyrosinase competitor, or melanin and other color bodies reducing composition.

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