Three Non-Phenolic Diarylheptanoids with Anti-Inflammatory Activity from Curcuma xanthorrhiza
摘要：
Bioassay-guided fractionation of a hexane extract of the rhizomes of CURCUMA XANTHORRHIZA Roxb. (Zingiberaceae) led to the isolation of three non-phenolic diarylheptanoids, identified mainly by high-field1H-NMR as TRANS-TRANS-1,7-diphenyl-1,3-heptadien-4-one (alnustone), TRANS-1,7-diprienyl-1-hepten-5-ol, and TRANS,TRANS-1,7-diphenyl-1,3-heptadien-5-ol. The latter is reported for the first time as a plant constituent. Germacrone, curzerenone, and cinnamaldehyde were also isolated and identified. The three diarylheptanoids all exerted significant anti-inflammatory activity in the assay of carrageenin-induced hind paw edema in rats.
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关键词：
Curcuma xanthorrhiza Zingiberaceae medicinal plant diarylheptanoids NMR anti inflammatory activity
DOI：
10.1055/s-2006-959730
被引量：
年份：
1993
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