Polyreactive IgM antibodies generated from autoimmune mice and selected for histone-binding activity
摘要：
A panel of -reactive IgM mAbs was obtained from belonging to various spontaneously autoimmune strains. Most of these were polyreactive, i.e. they showed to other cationic antigens (poly-L-lysine, , ) or to cytoskeletal (, myosin, ). The variable regions of these were encoded by V genes and gene segments belonging to various families. Their H chain third hypervariable regions were unusual in that the D segments were read in all three possible reading frames in contrast to most conventional and other polyreactive obtained from normal .
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DOI：
10.1093/intimm/4.10.1103
被引量：
年份：
1992
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