Anti-interleukin-5 therapy for asthma and hypereosinophilic syndrome.
摘要:
Interleukin 5 (IL-5) is a key cytokine in the regulation of eosinophilia and eosinophil activation in humans. Monoclonal antibodies to anti–IL-5 have become available for use in clinical studies in humans. This article discusses the rationale for the use of anti–IL-5 therapy in asthma and hypereosinophilic syndrome and summarizes the available clinical data on the use of anti–IL-5 to treat these disorders.
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DOI:
10.1016/j.iac.2004.06.007
被引量:
年份:
2004
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