Ulcerative Cystitis Associated with Ketamine

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摘要：

Ketamine is a clinically used dissociative anaesthetic that has become more widely used as a recreational drag. It causes a variety of negative effects in the cardiovascular and nervous systems.1 However, its genitor-urinary effects have rarely been investigated.2 In this article, we report three cases of ketamine-associated ulcerative cystitis.The first case is a 25-year-old single woman who was admitted to the hospital for acute-onset epigastric pain and urinary frequency for two days. She had two previous episodes of gastric ulcer disease but denied substance abuse at that time. On admission, the patient had hematuria and a burning sensation in the bladder. Panendoscopy showed only superficial gastritis and no peptic ulcer. Abnormal white blood cell count arid urinalysis were supportive of pyuria and hematuria but urine culture was negative. Abdominal computed tomography showed significant urinary bladder wall thickening with peri-vesical infiltrations. Cystoscopy revealed multiple erythema-tous swelling and necrotic mucosa in the bladder.

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关键词：

Ketamine Cystitis Bladder Ulcerative 氯胺酮膀胱炎膀胱

DOI：

10.1080/10550490802266243

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年份：

2010