Zebrafish Rho kinase 2 acts downstream of Wnt11 to mediate cell polarity and effective convergence and extension movements.
摘要：
Conclusions: During zebrafish gastrulation, Rok2 acts downstream of noncanonical Wnt11 signaling to mediate mediolateral cell elongation required for dorsal cell movement along straight paths. Furthermore, elongation and orientation of the cell body are independent properties that require both cell-autonomous and nonautonomous Rok2 function.
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关键词：
Animals Zebrafish Intracellular Signaling Peptides and Proteins Oligonucleotides Xenopus Proteins Glycoproteins Zebrafish Proteins Embryonic Development Signal Transduction Base Sequence
DOI：
10.1016/S0960-9822(02)00864-3
被引量：
年份：
2002
Elsevier
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Elsevier
国家科技图书文献中心
(权威机构)
万方医学
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