The renaissance of GSK3.
摘要:
Glycogen synthase kinase 3 (GSK3) was initially described as a key enzyme involved in glycogen metabolism, but is now known to regulate a diverse array of cell functions. The study of the substrate specificity and regulation of GSK3 activity has been important in the quest for therapeutic intervention.
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关键词:
Animals Humans Diabetes Mellitus, Type 2 Glycogen Insulin Glycogen Synthase Kinases Enzyme Inhibitors Signal Transduction Substrate Specificity Phosphorylation
DOI:
10.1038/35096075
被引量:
年份:
2001


































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