Enantioselective Friedel–Crafts alkylation of indoles with nitroalkenes catalyzed by a bis(oxazoline)–Cu(II) complex
摘要:
The catalytic enantioselective Friedel–Crafts reaction of indole with trans-β-nitrostyrene is reported in the presence of copper triflate–bisoxazoline complexes. The reaction furnished nitroalkylated indoles in excellent yields (up to 95%) and high enantioselectivities up to an 86% ee.
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DOI:
10.1016/j.tetlet.2006.12.081
被引量:
年份:
2007
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