Serotonin and octopamine in the nematode Caenorhabditis elegans

来自 NCBI

阅读量:

75

作者:

H HorvitzM ChalfieC TrentJ SulstonP Evans

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摘要:

The biogenic amines serotonin and octopamine are present in the nematode Caenorhabditis elegans. Serotonin, detected histochemically in whole mounts, is localized in two pharyngeal neurons that appear to be neurosecretory. Octopamine, identified radioenzymatically in crude extracts, probably is also localized in a few neurons. Exogenous serotonin and octopamine elicit specific and opposite behavioral responses in Caenorhabditis elegans, suggesting that these compounds function physiologically as antagonists.

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DOI:

10.1126/science.6805073

被引量:

921

年份:

1982

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2013
被引量:59

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