A new method of classifying prognostic comorbidity in longitudinal studies: development and validation.
摘要：
The objective of this study was to develop a prospectively applicable method for classifying comorbid conditions which might alter the risk of mortality for use in longitudinal studies. A weighted index that takes into account the number and the seriousness of comorbid disease was developed in a cohort of 559 medical patients. The 1-yr mortality rates for the different scores were: "0", 12% (181); "1–2", 26% (225); "3–4", 52% (71); and " 5", 85% (82). The index was tested for its ability to predict risk of death from comorbid disease in the second cohort of 685 patients during a 10-yr follow-up. The percent of patients who died of comorbid disease for the different scores were: "0", 8% (588); "1", 25% (54); "2", 48% (25); " 3", 59% (18). With each increased level of the comorbidity index, there were stepwise increases in the cumulative mortality attributable to comorbid disease (log rank χ 2 = 165; p < 0.0001). In this longer follow-up, age was also a predictor of mortality ( p < 0.001). The new index performed similarly to a previous system devised by Kaplan and Feinstein. The method of classifying comorbidity provides a simple, readily applicable and valid method of estimating risk of death from comorbid disease for use in longitudinal studies. Further work in larger populations is still required to refine the approach because the number of patients with any given condition in this study was relatively small.
展开
关键词：
Humans Breast Neoplasms Prognosis Epidemiologic Methods Morbidity Actuarial Analysis Risk Longitudinal Studies Follow-Up Studies Prospective Studies
DOI：
10.1016/0021-9681(87)90171-8
被引量：
年份：
1987
Taylor & Francis
Elsevier
BMJ
BMJ
Semantic Scholar
(全网免费下载)
查看更多
dx.doi.org
NCBI
Oxford Univ Press
BioMed Central
NCBI
Europe PMC
JSTOR
The Lancet
ResearchGate
ejinme.com
j-biomed-inform.com
clinicalmicrobiologyandinfection.com
urologiconcology.org
onAcademic
bloodjournal.org
pubs.rsna.org
fertstert.org
annemergmed.com
jem-journal.com
jabfm.org
haematologica.org
giejournal.org
asheducationbook.hematologylibrary.org
onlinecjc.ca
content.healthaffairs.org
jada.ada.org
ajhp.org
oarsijournal.com
cghjournal.org
redjournal.org
jurology.com
openres.ersjournals.com
futuremedicine.com
jamda.com
bprch.com
mayoclinicproceedings.org
psyneuen-journal.com
cfp.ca
pubfacts.com
ar.iiarjournals.org
dmidjournal.com
ptjournal.apta.org
ajog.org
aggjournal.com
deepdyve.com
science-open.com
pubmed.com
journalofinfection.com
heartfailure.onlinejacc.org
europeangeriaticmedicine.com
evidences.carpha.bvsalud.org
alzheimersanddementia.com
jacionline.org
geriatric.theclinics.com
rsap.org
annfammed.org
jcafulltextonline.com
gastrojournal.org
stroke.ahajournals.org
gnjournal.com
clinicaltherapeutics.com
eje-online.org
cmajopen.ca
ajkd.org
aaojournal.org
bjp.rcpsych.org
transplantation-proceedings.org
goldjournal.net
journalacs.org
oooojournal.net
seminoncol.org
internationaljournalofcardiology.com
e-jmii.com
SAGE
heartlungcirc.org
jnccn.org
cebp.aacrjournals.org
clinical-lung-cancer.com
appliedresearch.cancer.gov
jrheum.com
jclinepi.com
scienceopen.com
ijidonline.com
ajconline.org
bjj.boneandjoint.org.uk
ijaaonline.com
ccn.aacnjournals.org
care.diabetesjournals.org
ps.psychiatryonline.org
bjgp.org
mendeley.com
rsfs.royalsocietypublishing.org
journalofsurgicalresearch.com
ajicjournal.org
jco.ascopubs.org
aornjournal.org
jdcjournal.com
jrnjournal.org
amjmed.com
insectscience.org
clinicalnutritionjournal.com
nejm.org
valueinhealthjournal.com
Semantic Scholar
(全网免费下载)
通过文献互助平台发起求助，成功后即可免费获取论文全文。
相似文献
参考文献
引证文献
辅助模式
引用
文献可以批量引用啦~
欢迎点我试用！
