Signal-induced degradation of I kappa B alpha requires site-specific ubiquitination.
摘要：
Members of the nuclear factor (NF)-kappaB/Rel family transcription factors are induced during thymic selection and in mature T lymphocytes after ligation of the T cell antigen receptor (TCR). Despite these findings, disruption of individual NF-kappaB/Rel genes has revealed no intrinsic defect in the development of mature T cells, perhaps reflecting functional redundancy. To circumvent this...
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DOI：
10.1073/pnas.92.24.11259
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年份：
1995
Europe PMC
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ResearchGate
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pnas.org
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The National Academy of Sciences of the United States of America
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