Ankaflavin: a natural novel PPARγ agonist upregulates Nrf2 to attenuate methylglyoxal-induced diabetes in vivo
摘要：
► Ankaflavin (AK) acts as a novel natural PPARγ agonist to improve diabetes. ► AK promotes Nrf2 to elevate glyoxalase, thereby metabolizing methylglyoxal. ► AK prevents inflammation caused by methylglyoxal in rats.
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关键词：
Ankaflavin Advanced glycation end products Methylglyoxal Peroxisome proliferator-activated receptor-γ Nuclear factor erythroid-related factor 2 Free radicals
DOI：
10.1016/j.freeradbiomed.2012.09.025
被引量：
年份：
2012
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