IGF1 molecular anomalies demonstrate its critical role in fetal, postnatal growth and brain development.
摘要:
gene. Currently these patients can benefit from recombinant IGF-I which is now available for treatment. These observations demonstrate that the integrity of IGF-I signalling is important for normal growth and brain development.
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关键词:
IGF1IGF-I deficiency small for gestational age intrauterine growth restriction fetal growth microcephaly IGF-I treatment short stature brain development deafness
DOI:
10.1016/j.beem.2010.08.005
被引量:
年份:
2011
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