MicroRNA-29 regulates T-box transcription factors and interferon-γ production in helper T cells.
摘要:
miRNA -deficient Tcells exhibit cell-intrinsic defects in IFN-γ signaling Individual miRNAs independently rescue specific defects of miRNA-deficient Tcells miR-29 negatively regulates IFN-γ production in helper Tcells IFN-γ repression by miR-29 involves regulation of both T-bet and Eomes
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关键词:
Animals Mice, Inbred C57BL Mice, Knockout Mice T-Lymphocytes, Helper-Inducer Cells, Cultured MicroRNAs Proteins T-Box Domain Proteins Cell Differentiation
DOI:
10.1016/j.immuni.2011.07.009
被引量:
年份:
2011













































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