Redox Redux: Revisiting PTPs and the Control of Cell Signaling

阅读量:

126

作者:

NK Tonks

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摘要:

The architecture of the active site of members of the protein tyrosine phosphatase (PTP) superfamily renders these enzymes sensitive to reversible oxidation and inactivation. The importance of reversible oxidation of PTP superfamily members in controlling the signal output following an extracellular stimulus is discussed.

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DOI:

10.1016/j.cell.2005.05.016

被引量:

1278

年份:

2005

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来源期刊

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2010
被引量:138

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