The Directed Aldol Reaction

We examined two methods of combining catch-and-effort data from small geographic regions into large regulatory areas to estimate catch-per-unit-effort (CPU...

T Mukaiyama - Organic Reactions

Alkylation of the dianion of .beta.-keto esters

We examined two methods of combining catch-and-effort data from small geographic regions into large regulatory areas to estimate catch-per-unit-effort (CPU...

Weiler，Larry. - 《Journal of the American Chemical Society》

Total synthesis of (-)-salicylihalamide A.

[see structure]. A 16-step synthesis of the novel cytotoxin salicylihalamide A (1E) has been achieved in 3.3% overall yield using ring closing metathesis t...

Snider, Barry B.，F Song - 《Organic Letters》

ChemInform Abstract: Two-Directional Chain Synthesis and Terminus Differentiation

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a Chem...

CS Poss，SL Schreiber - 《Cheminform》

Inhibitors of protein tyrosine phosphatases: next-generation drugs?

The protein tyrosine phosphatases (PTPs) constitute a family of closely related key regulatory enzymes that dephosphorylate phosphotyrosine residues in the...

L Bialy，H Waldmann - 《Angew Chem Int Ed Engl》

Remote, 1,5-anti stereoinduction in the boron-mediated aldol reactions of β-oxygenated methyl ketones

High levels of 1,5-stereoinduction are obtained in the boron-mediated aldol reactions of β-oxygenated methyl ketones 5,7 and 8 with achiral aldehydes. The aldol products undergo stereoselective reductions, providing an efficient method ...

Ian Paterson and Karl R. Gibson and Renata M. Oballa - 《Tetrahedron Letters》

Toward the total synthesis of spirastrellolide A. Part 1: Strategic considerations and preparation of the southern domain

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a Chem...

A Fürstner，MD Fenster，B Fasching，... - 《Cheminform》

ChemInform Abstract: THE DIRECTED ALDOL REACTION

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a Chem...

T Mukaiyama - 《Chemischer Informationsdienst》

Asymmetric hydrogenation of .beta.-keto carboxylic esters. A practical, purely chemical access to .beta.-hydroxy esters in high enantiomeric purity

Hydrogenation reactions of β-keto esters (I), (III), (V) catalyzed by the Ru(II) complexes shown in the scheme under an initial H 2 pressure of 50-100 at...

R Noyori，T Ohkuma，M Kitamura，... - 《Cheminform》

Alkylation of dianions of .beta.-keto esters

The dianions from a variety of β-keto esters have been generated using 1 equiv of sodium hydride and 1 equiv of n-butyllithium or methyllithium or 2 equiv of lithium diisopropylamide. The dianions react with a range of alkylating agents...

SN Huckin，L Weiler - 《Journal of the American Chemical Society》