New pharmaceutical forms for administration of medicaments by oral route, with programmed release
申请(专利)号:
US19850750980
申请日期:
1985-07-01
公开/公告号:
US4609542A
公开/公告日期:
1986-09-02
申请(专利权)人:
ELAN CORPORATION, P.L.C.
被引量:
摘要:
The present invention relates to a new pharmaceutical form for oral use in the nature of delayed action and controlled absorption medicaments. This form comprises an association of miniaturized granules obtained by high to very high compression: (a) with pH control agents, (b) coated with excipients determining the slow penetration of digestive and/or (c) coated with a very thin layer of lipids. These miniaturized granules may contain glucose, nay have pH control agents with different solubilities, and may be in the form of miniaturized granules with a pH gradient.
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