Oesophageal cancer studies in the caspian littoral of Iran: Some residual results, including opium use as a risk factor

来自 EBSCO

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作者：

P.，Ghadirian，G.，F.，Stein，C.，Gorodetzky，M.，B.，Roberfroid

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摘要：

A study was conducted in northern Iran in areas of very high, high and moderately low incidence of oesophageal cancer. Morphine metabolites in urine as an indicator of opium use, and a variety of nutritional and biochemical measures, including salivary antipyrine half-life, were determined in households with a case of oesophageal cancer and in control households. Results on 1,590 individuals showed that the prevalence of appreciable levels (≤ 1μ/ml) of urinary morphine metabolites was much higher in areas of high and very high incidence of oesophageal cancer than in low-incidence areas, particularly for those under age 50 years in both sexes, where a 6-fold difference was seen. Members of households with a case of oesophageal cancer had a higher prevalence of positive urinary morphine metabolite findings than members of control households from the same village. Salivary antipyrine half-life (AP-T 1/2), as a measure of hepatic drug metabolizing capacity, was estimated in 120 subje

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DOI：

10.1002/ijc.2910350505

被引量：

356

年份：

1985