Membrane fusion
摘要：
Common themes are emerging from the study of viral, cell-cell, intracellular, and liposome fusion. Viral and cellular membrane fusion events are mediated by fusion proteins or fusion machines. Viral fusion proteins share important characteristics, notably a fusion peptide within a transmembrane-anchored polypeptide chain. At least one protein involved in a cell-cell fusion reaction resembles viral fusion proteins. Components of intracellular fusion machines are utilized in multiple membrane trafficking events and are conserved through evolution. Fusion pores develop during viral and intracellular fusion events suggesting similar mechanisms for many, if not all, fusion events.
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关键词：
Golgi Apparatus Mast Cells Intracellular Membranes Cytoplasmic Granules Viral Fusion Proteins Biological Transport Exocytosis Membrane Fusion Molecular Structure Virus Physiological Phenomena
DOI：
10.1021/cr000036+
被引量：
年份：
1992
Semantic Scholar
万方医学
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