DNA sequences to target proteins to the mammary gland for efficient secretion
申请(专利)号:
AU19880011784
申请日期:
1988-02-17
公开/公告号:
AU1178488A
公开/公告日期:
1988-08-18
申请(专利权)人:
GENE PHARMING EUROPE BV
被引量:
摘要:
Described is a method of targeting specific genes to the mammary gland which results in the efficient synthesis and secretion of biologically important molecules. Further, there is described as a composition of matter, a transgenic mammal having the ability to reproduce itself and being suitable for the secretion of biologically active agents into its milk. Additionally there is disclosed as a composition of matter, recombinant DNA gene complexes designed to integrate into a mammalian genome and to synthesize and secrete biological active agents into the milk. Furthermore methods of producing and using altered milk are disclosed.
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