摘要：

3-Chlorobenzopyrano[2,3- c]pyrazole ( 2) was prepared and reacted with sodium azide to give compound 3, whereas its reaction with benzoyl hydrazide, ethyl glycinate, anthranilic acid or o-phenylenediamine afforded the products 4– 7, respectively. Compounds 8 and 9 were synthesized by the reaction of compound 2 with 2-mercaptobenzothiazole or piperidine. 3-Hydrazinobenzopyrano[2,3- c]pyrazole ( 10) was obtained and subjected to cyclization with different reagents such as CS 2, benzoic acid, acetyl acetone and diethyl malonate to give compounds 11– 14, respectively. Compound 10 was cyclized also with phenacyl cyanide, ylidenemalononitriles to afford the products 15– 20, respectively. On the other hand, compound 10 was cyclized with 3-[bis(methylthio)methylene]pentane-2,4-dione or 1,1-dicyano 2,2-dimethylthioethylene to give the corresponding compounds 22 and 23 which in turn were reacted with some compounds containing active methylene groups to afford the corresponding compounds 24– 27, respectively. The biological activities of some selected compounds were given.

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