Viral pathogenicity determinants are suppressors of transgene silencing
摘要：
Post-transcriptional gene silencing (PTGS) of a green fluorescent protein (GFP) transgene is suppressed in Nicotiana benthamiana plants infected with potato virus Y (PVY) or with cucumber mosaic virus (CMV), but not in plants infected with potato virus X (PVX). By expressing PVY and CMV-encoded proteins in a PVX vector we have shown that the viral suppressors of gene silencing are the HCPro of PVY and the 2b protein of CMV. The HCPro acts by blocking the maintenance of PTGS in tissues where silencing had already been set, whereas the 2b protein prevents initiation of gene silencing at the growing points of the plants. Combined with previous findings that viruses are both activators and targets of PTGS, these data provide compelling evidence that PTGS represents a natural mechanism for plant protection against viruses.
展开
DOI：
10.1093/emboj/17.22.6739
被引量：
年份：
1998
EBSCO
Wiley
万方医学
Semantic Scholar
(全网免费下载)
Semantic Scholar
查看更多
dx.doi.org
Oxford Univ Press
Cell Press
NCBI
Europe PMC
(全网免费下载)
Europe PMC
NCBI
JBC
AGRIS
ResearchGate
(全网免费下载)
ProQuest
ResearchGate
EureKaMag.com
(全网免费下载)
EBSCO
EBSCO
vir.sgmjournals.org
rstb.royalsocietypublishing.org
199.171.202.195
deepdyve.com
genesdev.cshlp.org
scholarbank.nus.sg
science-open.com
scholarbank.nus.edu.sg
core.ac.uk
emboj.embopress.org
(全网免费下载)
SAGE
scienceopen.com
d.scholar.cnki.net
pubfacts.com
readcube.com
mysciencework.com
mmbr.asm.org
pnas.org
onAcademic
emboj.embopress.org
plantcell.org
mendeley.com
plantphysiol.org
embojnl.embopress.org
(全网免费下载)
Semantic Scholar
(全网免费下载)
Europe PMC
(全网免费下载)
EureKaMag.com
(全网免费下载)
ResearchGate
(全网免费下载)
emboj.embopress.org
(全网免费下载)
embojnl.embopress.org
(全网免费下载)
通过文献互助平台发起求助，成功后即可免费获取论文全文。
相似文献
参考文献
引证文献
辅助模式
引用
文献可以批量引用啦~
欢迎点我试用！
