摘要：

The fluorinated benzodiazepine compound Ro 5–4200 was used to induce anaesthesia in 140 patients. Eighty women coming for standard radical hysterectomy were induced with the drug to test its effect on amnesia, requirement of muscle relaxant and post-operative vomiting. The duration of sleep was tested in 20 women undergoing short gynaecological procedures. To observe its effect on a pathological cardio-vascular system, 40 patients with cardiac function corresponding to class 2–4, coming for open heart surgery, were induced with it. Comparable series were run with thiopentone and diazepam.

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