Electron microscopy reveals that transcription factor TFIIIA bends 5S DNA.
摘要:
We have used a high-resolution analytical electron microscopic technique, electron spectroscopic imaging, to study the in vitro interaction between the transcription factor IIIA (TFIIIA) and 5S ribosomal gene DNA. The images and analytical measurements support our proposal that the helix axis is bent by the protein into a hairpin-shaped configuration.
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关键词:
basic biological sciences inorganic, organic, physical and analytical chemistry dna biochemical reaction kinetics ribosomes genes transcription factors configuration electron microscopy images
DOI:
10.1128/MCB.9.1.336
被引量:
年份:
1989
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