Distribution of transferrin, ferritin, and lactoferrin in human tissues.
摘要:
An immunoperoxidase staining technique was used for detecting three major iron-binding proteins (transferrin, ferritin, and lactoferrin) in routine histological paraffin sections of human tissue. Transferrin was found mainly in hepatocytes, a variety of epithelial and myoepithelial cells, renal tubular cells, and histiocytes. Ferritin was most readily found in histiocytes and liver cells, with weaker reactions seen in epithelial cells. Lactoferrin was found in lactating breast tissue, bronchial glands, polymorphs, and gastric and duodenal epithelial cells. The technique is potentially valuable for investigating abnormal iron states.
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关键词:
Liver Humans Gastrointestinal Diseases Skin Diseases Transferrin Lactoferrin Lactoglobulins Immunoenzyme Techniques Tissue Distribution Pregnancy
DOI:
10.1136/jcp.31.4.316
被引量:
年份:
1978
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