摘要：

Objective To investigate the eperession of bcl 2 ,bax and Ki 67 in human gastric carcinoma and its clinical implication.Methods bcl 2,bax and Ki 67 expressuons were detected in 70 cases of human gastric carcinoma using immunohistochemical techniques.Results bcl 2 was expressed in 21 43% of gastric carcinoma.Compared with non cancerous gastric mucosa,the bax expression was significantly decreased in gastric carcinoma.A trend of increasing Ki 67 index with depth of invasion was noted.The Ki 67 index in GC with lymph nodes metastasis(INM)was significantly higher than that without LNM.Conclusion The unssual expression of bcl 2 may play certain roleted to its poor response to its poor response to chemotherapeutic treatment.Ki 67 expression may be a good marker relating to tumor progression and prognosis.$$$$

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