Campylobacter pylori detected noninvasively by the 13C-urea breath test.
摘要：
The high endogenous urease activity of Campylobacter pylori was exploited in a non-invasive test for the presence of this organism in the stomach. When 13C-urea was administered orally after a test meal, urea-derived 13CO 2 appeared in the respiratory CO 2 of infected individuals at a constant rate for >100 min. The test was validated in 26 individuals who underwent both the 13C-urea breath test and endoscopic biopsy of the antral mucosa for culture and histological examination. Each positive breath test proved to be correlated with a positive culture or Warthin-Starry silver stain of a mucosal biopsy specimen, or both.
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关键词：
Humans Pyloric Antrum Campylobacter Infections Gastritis Carbon Dioxide Carbon Isotopes Urea Urease Adult Evaluation Studies as Topic
DOI：
10.1016/S0140-6736(87)92145-3
被引量：
年份：
1987
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