Lipid Modifications of Trimeric G Proteins
摘要：
G protein alpha subunits and beta gamma dimers are covalently modified by lipids. The emerging picture is one in which attached lipids provide more than just a nonspecific "glue" for sticking G proteins to membranes. We are only beginning to understand how different lipid modifications of different G protein subunits affect specific protein-protein interactions and localization to specific cellular sites. In addition, regulation of these modifications, particularly palmitoylation, can provide new ways to regulate signals transmitted by G proteins.
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关键词：
GTP Binding Proteins Lipids Amino Acid Sequence Molecular Sequence Data Myristic Acid Myristic Acids Palmitic Acid Palmitic Acids Protein Isoprenylation
DOI：
10.1074/jbc.270.2.503
被引量：
年份：
1995
Taylor & Francis
Elsevier
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万方医学
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