摘要：

The obliteration of the sinus frontalis after removal of the chronically inflamed and irreversibly transformed mucous is a common surgical treatment. There is no definite answer to the question of the most suitable material for obliteration. The suitability of the Kieler Knochenspan was, therefore, tested in animal experiments. After trepanation and removal of the mucous of the bulla of 30 guinea pigs, the cave was filled up with Kieler Knochenspan. The animals were killed 2 weeks, 1, 2, 3, and 4 months after implantation. The implanted nonvital spongy substance of the Kieler Knochenspan was first enclosed in granulation tissue. Then, depending on the duration of implantation, this granulation tissue turns into bony substance first peripherically and then centrally. Immunologically conditioned reactions were never observed. Thus, the transformation of the Kieler Knochenspan in the pneumatic system of the guinea pig is the same as in human tubular bones. So the conclusion is drawn that Kieler Knochenspan might be used in the obliteration of the human frontal sinus.

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