Cdk inhibitors: on the threshold of checkpoints and development.
摘要:
The regulation of cyclin-dependent kinases is at the heart of cell cycle control and, by inference, the control of cell proliferation. Recent advances in regulation of these kinases have uncovered a group of small proteins that bind to and inhibit them, thus preventing cell cycle progression. Linking these proteins to tumor suppressor functions has provided a much sought after connection between cancer and cell cycle control.
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关键词:
LEAD CADMIUM COBALT SINGLE CHANNEL PATCH CLAMP CALCIUM-ACTIVATED POTASSIUM CHANNEL HUMAN ERYTHROCYTE N1E-115 MOUSE NEUROBLASTOMA CELL
DOI:
10.1016/0955-0674(94)90055-8
被引量:
年份:
1994
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