MIP-1alpha and MCP-1 contribute to crescents and interstitial lesions in human crescentic glomerulonephritis.
摘要:
These observations suggest that locally produced MIP-1α may be involved in the development of cellular crescents in the acute phase via CCR5 and that MCP-1 may be involved mainly in the development of interstitial lesions in the chronic phase when fibrocellular/fibrous crescents are present, possibly through Mϕ recruitment and activation.
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关键词:
macrophage inflammatory protein-1 monocyte chemoattractant protein-1 cellular crescents rapidly progressive glomerulonephritis CCR5
DOI:
10.1046/j.1523-1755.1999.00646.x
被引量:
年份:
1999





























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