Phenol ethers

阅读量:

57

作者:

PMJ ManouryIAG CaveroH NajerDPRL Giudicelli

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摘要:

The invention provides phenol ethers of the formula: ##STR1## wherein R is branched C 3 -4 alkyl, C 3 -4 cycloalkyl, branched cyano(C 3 -4 alkyl), phenyl(C 2 -3 alkyl), halophenyl(C 2 -3 alkyl), (C 1 -4 alkoxy)phenyl(C 2 -4 alkyl), or (C 1 -4 acyl)amino(C 1 -4 alkyl), alk is C 1 -4 alkyl substituted by a 3 to 6 membered cycloalkyl group, X is --O--, --S-- or --SO 2 --; and R 1 is --C 1 -4 alkyl- or --C 1 -4 alkoxy-, in their racemic and optically active forms, and their addition salts with pharmaceutically acceptable acids. These compounds are useful in therapy as β-adrenergic blocking agents. Intermediates are also provided.

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DOI:

US4311708 A

被引量:

81

年份:

1982

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