The TRPM8 channel forms a complex with the 5-HT 1B receptor and phospholipase D that amplifies its reversal of pain hypersensitivity
摘要：
A subset of sensory neurons co-express TRPM8 ion channels and 5-HT1B receptors.TRPM8 and 5-HT1BRs form molecular complexes that also incorporate phospholipase D.5-HT1BRs signal through PLD and PIP2 to potentiate TRPM8 activation.5-HT1BRs amplify TRPM8 attenuation of pain-associated synaptic hypersensitivity.5-HT1BRs amplify TRPM8 analgesia in behavioural models of chronic pain.
展开
DOI：
10.1016/j.neuropharm.2013.11.006
被引量：
年份：
2014
Elsevier
Elsevier
(全网免费下载)
国家科技图书文献中心
(权威机构)
Semantic Scholar
Semantic Scholar
(全网免费下载)
查看更多
dx.doi.org
Europe PMC
NCBI
ResearchGate
Citeseer
(全网免费下载)
EBSCO
www-test.pure.ed.ac.uk
(全网免费下载)
学术范
research.ed.ac.uk
(全网免费下载)
pubfacts.com
学术范
(全网免费下载)
deepdyve.com
painresearchforum.org
onAcademic
research.ed.ac.uk
mysciencework.com
www.socolar.com
Elsevier
(全网免费下载)
Semantic Scholar
(全网免费下载)
Citeseer
(全网免费下载)
www-test.pure.ed.ac.uk
(全网免费下载)
research.ed.ac.uk
(全网免费下载)
学术范
(全网免费下载)
通过文献互助平台发起求助，成功后即可免费获取论文全文。
请先登入
相似文献
参考文献
引证文献
辅助模式
0
引用
文献可以批量引用啦~
欢迎点我试用！
