Design, synthesis and anti-microbial activity of 1H-pyrazole carboxylates
摘要:
In a SAR study, we have synthesized a few 1H-pyrazole carboxylate related microbicides using Vilsmeier reagent. The anti-microbial screening results of 1H-pyrazole-3-carboxylate are reported here for the first time. The effect of 1H-pyrazole carboxylates on the mycelial growth of plant pathogenic fungi is revealed. The first X-ray structure in the family of microbicidal 1H-pyrazole-4-carboxylates is presented.
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关键词:
1H-Pyrazole carboxylate Vilsmeier reagent Anti-microbial screening Plant pathogenic fungi Human pathogenic bacteria
DOI:
10.1016/j.bmcl.2004.09.066
被引量:
年份:
2004
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