摘要：

Shows that plasmin reductase isolated from conditioned medium of fibrosarcoma cells is the glycolytic enzyme phosphoglycerate kinase. Administration of phosphoglycerate kinase to tumor-bearing mice causing an increase in plasma levels of angiostatin and a decrease in tumor vascularity and rate of tumor growth; Indication that phosphoglycerate kinase functions in glycolysis and is secreted by tumor cells and participates in the angiogenic process as a disulphide reductase.

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