Studies of drugs given before anaesthesia. 18. The synthetic opiates.
摘要：
SUMMARY The sedative and toxic properties of eleven synthetic analgesics (levorphanol, phenazocine, pentazocine, pethidine, anileridine, phenoperidine, fentanyl, methadone, dipipanone, dextromoramide and phenadoxone) have been determined by giving them, in a double-blind trial, as pre-anaesthetic medication to a standard female population. Levorphanol produced the best sedation while phenoperidine, dipipanone and dextromoramide were also effective in calming the patient. Fentanyl was least efficient in this respect. Pethidine and fentanyl were the most toxic drugs while pentazocine and dipipanone showed least toxicity.
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关键词：
Humans Tachycardia Hypotension Nausea Dextromoramide Meperidine Phenoperidine Levorphanol Analgesics Preanesthetic Medication
DOI：
10.1093/bja/41.11.987
被引量：
年份：
1969
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