Role of appendicitis and appendectomy in the pathogenesis of ulcerative colitis: a critical review.

Besides a genetic predisposition, a causal role of various environmental factors has been considered in the etiology of ulcerative colitis (UC). The associ...

IE Koutroubakis，IG Vlachonikolis，EA Kouroumalis - 《Inflammatory Bowel Diseases》

Distinct roles for B7-1 (CD-80) and B7-2 (CD-86) in the initiation of experimental allergic encephalomyelitis.

The activation and differentiation of T cells require both antigen/MHC recognition and costimulatory signals. The present studies examined the role of B7-1...

Racke, M. K，Scott, D. E，L Quigley，... - 《Journal of Clinical Investigation》

Dual role of alpha-defensin-1 in anti-HIV-1 innate immunity.

Journal of Clinical InvestigationChang TL, Vargas J Jr, DelPortillo A, Klotman ME (2005) Dual role of alpha-defensin-1 in anti-HIV-1 innate immunity...

TL Chang，VJ Jr，A Delportillo，... - 《Journal of Clinical Investigation》

Central Role for B Lymphocytes and CD4+ T Cells in Immunity to Infection by the Attaching and Effacing Pathogen Citrobacter rodentium

Citrobacter rodentium, an attaching-effacing bacterial pathogen, establishes an acute infection of the murine colonic epithelium and induces a mild colitis...

CP Simmons，S Clare，M Ghaem-Maghami，... - 《Infection & Immunity》

Toll-like receptors in innate immunity: role of bacterial endotoxin and toll-like receptor 4 in endometrium and endometriosis.

immunity:role of bacterial endotoxin and toll-like receptor 4 in endometrium and endometriosis [J].Gynecologic and Obstetric Investigation,2009,68(1):40-52...

KN Khan，M Kitajima，K Hiraki，... - 《Gynecologic & Obstetric Investigation》

A novel immune-to-CNS communication pathway: Cells of the meninges surrounding the spinal cord CSF space produce proinflammatory cytokines in response to a...

Pain is enhanced in response to elevations of proinflammatory cytokines in spinal cerebrospinal fluid (CSF), following either intrathecal injection of thes...

J Wieseler-Frank，BM Jekich，JH Mahoney，... - 《Brain Behavior & Immunity》

Gastro-intestinal toxicity of chemotherapeutics in colorectal cancer:The role of inflammation

Chemotherapy-induced diarrhea(CID)is a common and often severe side effect experienced by colorectal cancer(CRC)patients during their treatment.As chemothe...

Chun，Seng，Lee，... - 《世界胃肠病学杂志(英文版)》

Leishmania donovani-Induced Ceramide as the Key Mediator of Akt Dephosphorylation in Murine Macrophages: Role of Protein Kinase Cζ and Phosphatase

Leishmania donovani is an intracellular protozoan parasite that impairs the host macrophage immune response to render it suitable for its survival and esta...

R Dey，N Majumder，S Bhattacharjee，... - 《Infection & Immunity》

The role of vitamin E in T-cell differentiation and the decrease of cellular immunity with aging

Leishmania donovani is an intracellular protozoan parasite that impairs the host macrophage immune response to render it suitable for its survival and esta...

Moriguchi，Satoru，Hamada，... - 《Journal of Medical Investigation Jmi》