Cloned and expressed nitric oxide synthase structurally resembles cytochrome P-450 reductase
摘要：
Nitric oxide is a messenger molecule, mediating the effect of endothelium-derived relaxing factor in blood vessels and the cytotoxic actions of macrophages, and playing a part in neuronal communication in the brain. Cloning of a complementary DNA for brain nitric oxide synthase reveals recognition sites for NADPH, FAD, flavin mononucleotide and calmodulin as well as phosphorylation sites, indicating that the synthase is regulated by many different factors. The only known mammalian enzyme with close homology is cytochrome P-450 reductase.
展开
关键词：
Cerebellum Cell Line Animals Humans Rats Flavin-Adenine Dinucleotide Flavin Mononucleotide NADP Amino Acid Oxidoreductases NADPH-Ferrihemoprotein Reductase
DOI：
10.1016/0962-8924(91)90032-5
被引量：
年份：
1991
Elsevier
BMJ
Nature
(全网免费下载)
Nature
万方医学
查看更多
dx.doi.org
Europe PMC
NCBI
Oxford Univ Press
NCBI
AACR
JBC
adsabs.harvard.edu
ProQuest
ResearchGate
EBSCO
EBSCO
plantphysiol.org
jacionline.org
jleukbio.org
fertstert.org
genesdev.cshlp.org
onlinecjc.ca
press.endocrine.org
jneurosci.org
clinchem.org
SAGE
hyper.ahajournals.org
jhu.pure.elsevier.com
bbs.sciencenet.cn
(全网免费下载)
diabetes.diabetesjournals.org
oarsijournal.com
erc.endocrinology-journals.org
ajp.psychiatryonline.org
ashjournal.com
intl.pharmrev.org
jimmunol.org
mendeley.com
molpharm.aspetjournals.org
dev.biologists.org
jap.physiology.org
laskerfoundation.org
biochemj.org
frontiersin.org
gastrojournal.org
jasn.asnjournals.org
cghjournal.org
Nature
(全网免费下载)
bbs.sciencenet.cn
(全网免费下载)
通过文献互助平台发起求助，成功后即可免费获取论文全文。
相似文献
参考文献
引证文献
辅助模式
引用
文献可以批量引用啦~
欢迎点我试用！
