Both a monoclonal antibody and antisera specific for determinants unique to individual cloned helper T cell lines can substitute for antigen and antigen-pr...

Two antisera and a monoclonal antibody raised in BALB.K mice against cloned, major histocompatibility complex (MHC)-restricted, antigen-specific helper T c...

Kaye，J. - 《Journal of Experimental Medicine》

The major histocompatibility complex-restricted antigen receptor on T cells in mouse and man: Identification of constant and variable peptides

The variability of the MHC restricted receptor on murine T cells was examined by comparing tryptic peptide fingerprints of the receptor isolated four three...

J Kappler，R Kubo，K Haskins，... - 《Cell》

Human cell surface glycoprotein related to cell proliferation is the receptor for transferrin

A cell surface glycoprotein antigen with an apparent molecular weight of about 100,000 that is selectively expressed on proliferating cells was purified fr...

IS Trowbridge，MB Omary - 《Proc Natl Acad Sci U S A》

Clonotypic structures involved in antigen-specific human T cell function. Relationship to the T3 molecular complex.

Monoclonal antibodies were produced against a human cytotoxic T cell clone, CT8III (specificity: HLA-A3), with the view of defining clonally restricted (cl...

Meuer，S. C. - 《Journal of Experimental Medicine》

Surface-specific iodination of membrane proteins of viruses and eucaryotic cells using 1,3,4,6-tetrachloro-3α,6α-diphenylglycoluril

Monoclonal antibodies were produced against a human cytotoxic T cell clone, CT8III (specificity: HLA-A3), with the view of defining clonally restricted (cl...

Mary Ann K. Markwell，C. Fred Fox - 《Biochemistry》

Identification and nucleotide sequence of a diversity DNA segment (D) of immunoglobulin heavy-chain genes

A putative diversity segment of immunoglobulin heavy-chain genes (D segment) has been identified 700 base pairs 5′ to J H1 DNA on the germ-line genome of the mouse. This 10-base pair D segment is flanked by two sets of sequences relate...

H Sakano，Y Kurosawa，M Weigert，... - 《Nature》

ANTIGEN RECOGNITION BY H-2RESTRICTED T CELLS

Summary We examined the effect of mutations in the V/3 portion of a pigeon cytochrome c (cyto c)-specific V/33 +/Vcz11 + T cell receptor on its ability to recognize cyto c/IE k and various superantigens. The results were consistent with ...

Shimonkevitz，R. - 《Journal of Experimental Medicine》

Identification of D segments of immunoglobulin heavy-chain genes and their rearrangement in T lymphocytes.

The finding that the diversity (D) and joining (JH) but not the variable (VH) DNA segments of mouse immunoglobulin heavy-chain genes are joined in the DNA ...

Kurosawa，V Boehmer，Haas，... - 《Nature》

Quantitative analysis of high-resolution trypsin-Giemsa bands on human prometaphase chromosomes

We have constructed ideograms of human prometaphase chromosomes from synchronized and from standard 72-h lymphocyte cultures. G banding was achieved by a trypsin-Giemsa (or Wright's stain) method. In addition to light (white) and dark (b...

U Francke，Nolynn Oliver - 《Human Genetics》

Alloreactivity of an antigen-specific T-cell clone

The apparent high frequency of alloreactive T cells has suggested that the two subpopulations—T cells specific for soluble protein antigens and alloreactive T cells—must overlap 1–3 . However, the existence of a set of germ-line genes...

B Sredni，RH Schwartz - 《Nature》