Enantioselective Organocatalytic Hydride Reduction
摘要：
The first enantioselective organocatalytic hydride reduction has been accomplished. The use of iminium catalysis has provided a new organocatalytic strategy for the enantioselective reduction of beta,beta-substituted alpha,beta-unsaturated aldehydes to generate beta-stereogenic aldehydes. The use of imidazolidinone 2 as the asymmetric catalyst has been found to mediate the transfer of hydrogen to a large class of enal substrates from ethyl Hantzsch ester. The capacity of catalyst 2 to accelerate E-Z isomerization prior to selective E-olefin reduction allows the implementation of geometrically impure enals in this operationally simple protocol.
展开
关键词：
aldehydes (benzene compounds diastereoselective syntheses, enantioselective syntheses (incl. cis/trans‐isomerism aldehydes (acyclic compounds cyclohexane derivatives
DOI：
10.1002/chin.200523079
被引量：
年份：
2005
ACS
(全网免费下载)
Wiley
ACS
(全网免费下载)
Semantic Scholar
万方医学
查看更多
Semantic Scholar
(全网免费下载)
dx.doi.org
Europe PMC
NCBI
NCBI
dialnet.unirioja.es
ResearchGate
EBSCO
EBSCO
infona.pl
mendeley.com
deepdyve.com
chemlabs.princeton.edu
(全网免费下载)
s3-eu-west-1.amazonaws.com
(全网免费下载)
readcube.com
pubfacts.com
princeton.edu
(全网免费下载)
organic-chemistry.org
mysciencework.com
onAcademic
pubget.com
ACS
(全网免费下载)
ACS
(全网免费下载)
Semantic Scholar
(全网免费下载)
princeton.edu
(全网免费下载)
chemlabs.princeton.edu
(全网免费下载)
s3-eu-west-1.amazonaws.com
(全网免费下载)
通过文献互助平台发起求助，成功后即可免费获取论文全文。
相似文献
参考文献
引证文献
引用走势
辅助模式
引用
文献可以批量引用啦~
欢迎点我试用！
