Effects of Exenatide on Systolic Blood Pressure in Subjects With Type 2 Diabetes
摘要：
BACKGROUND: The majority of patients with type 2 diabetes mellitus have blood pressure (BP) exceeding the recommended value of or = 130 mm Hg (difference of -3.8 mm Hg (1.08) from placebo: P = 0.0004; difference of -4.0 mm Hg (1.01) from insulin; P /=150 mm Hg. Similar responses were observed in African-American subjects. A weak correlation between the amount of weight lost and reduction in SBP was found (r = 0.09, P = 0.002) for exenatide-treated subjects. CONCLUSIONS: These results support the need for a prospective, randomized, controlled study of BP changes during exenatide treatment in patients with hypertension and type 2 diabetes.
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关键词：
African American blood pressure diabetes exenatide GLP-1 hypertension insulin placebo weight loss
DOI：
10.1038/ajh.2009.245
被引量：
年份：
2010
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