Asymmetric Synthesis of Piperidines and Octahydroindolizines

阅读量:

19

摘要:

The conjugate addition of a homochiral lithium amide to a ξ-hydroxy-α,β-unsaturated ester, followed by a one-pot, ring-closure-N-debenzylation protocol has been used in the asymmetric syntheses of (S)-coniine and (R)-δ-coniceine (isolated as the corresponding hydrochloride salts) and the bicyclic core of stellettamide A.

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DOI:

10.1055/s-0029-1219346

被引量:

30

年份:

2010

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2012
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