Effects of Spatholobus Suberectus Dunn on The Contraction of Rat Aortic Ring
摘要:
The mechanism of vasodilator action of extracts from Spatholobus Suberectus Dunn(SS) was studied with isolated rat aortic rings. The results indicated that SS caused the rightward shifting of the dose response curves in Phe, KCl and CaCl 2 , and depressed their maximal responses. SS obviously relax the contraction induced by Phe depending extracellular Calcium, but had no obvious effect on the intracellular Calcium dependent contraction caused by Phe. These results suggest that the mechanism of vasodilatation of SS may be related with the inhibition of the potential dependent Calcium channel and/or receptor operated Calcium channel.
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关键词:
spatholobus suberectus dunn ring of aorta calcium channel blockers phenylephrine potassium chloride
被引量:
年份:
1996
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