TABLET DISINTEGRATING IN THE ORAL CAVITY
申请(专利)号:
WO2006JP301951
申请日期:
2006-02-06
公开/公告号:
WO2006085497A1
公开/公告日期:
2006-08-17
申请(专利权)人:
KISSEI PHARMACEUTICAL CO., LTD.;MIMURA, KAZUKI;KANADA, KEN;OUCHI, KIYOHISA
被引量:
摘要:
It is intended to provide a tablet, which quickly disintegrates in the oral cavity, has an appropriate hardness and is suitable for the production on the industrial scale, and a method of producing the same. Namely, a tablet disintegrating in the oral cavity which comprises a) an active ingredient, b) a sugar or a sugar alcohol, c) a partly gelatinized starch containing from 10 to 20% by weight of matters soluble in cold water, and d) a disintegrating agent. The tablet disintegrating in the oral cavity as described above can be produced by blending the disintegrating agent with a granular mixture consisting of the active ingredient a), the sugar or the sugar alcohol b) and the partly gelatinized starch containing from 10 to 20% by weight of matters soluble in cold water c) followed by compression molding.
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