Synthesis of 4-vinylindoles using ruthenium-catalyzed ring-closing enyne metathesis.
摘要：
The selective synthesis of substituted 4-vinylindoles by the ring-closing enyne metathesis (RCEM)/dehydration sequence is reported. In contrast with many known methods in which a pyrrole ring is constructed onto a functionalized benzene precursor, this method enables the construction of a benzene ring onto a pyrrole precursor. The RCEM/tautomerization sequence for the synthesis of 7-hydroxy-4-vinylindole is also presented as an application of this method.
展开
关键词：
indole derivatives, isoindole derivatives metathesis reactions ring closure reactions catalysis, phase‐transfer catalysis
DOI：
10.1021/jo400099x
被引量：
年份：
2013
相似文献
参考文献
引证文献
辅助模式
引用
文献可以批量引用啦~
欢迎点我试用！
